Antigenic variation in current human type A influenzaviruses: Antigenic characteristics of the variants and their geographic distribution
Identifieur interne : 000203 ( 1968/Analysis ); précédent : 000202; suivant : 000204Antigenic variation in current human type A influenzaviruses: Antigenic characteristics of the variants and their geographic distribution
Auteurs : G. C. Schild ; M. Henry-Aymard ; M. S. Pereira ; P. Chakraverty ; W. Dowdle ; M. Coleman ; W. K. ChangSource :
- Bulletin of the World Health Organization [ 0042-9686 ] ; 1973.
Abstract
Outbreaks of influenza due to the virus A/Hong Kong/1/68 (H3N2) began in 1968 and are still occurring. The haemagglutinin of this virus is different from that of the A/Singapore/1/57 virus (the “Asian” strain) but the neuraminidase antigens are the same. Between 1968 and 1971 only minor antigenic “drift” in the haemagglutinin was noted, but in recent months 2 isolates have been identified in which considerable “drift” has occurred in the haemagglutinin and in the neuraminidase antigens. One, A/Hong Kong/5/72 (H3N2), was first detected in outbreaks in Hong Kong between November 1971 and January 1972 and was predominant there and in Korea but did not become widely disseminated. The second strain, A/England/42/72 (H3N2), has been isolated in winter outbreaks in the southern hemisphere and now appears to be the predominant strain in the northern hemisphere. The characteristics of the strains are described.
Url:
PubMed: 4200741
PubMed Central: 2481068
Affiliations:
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PMC:2481068Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Antigenic variation in current human type A influenzaviruses: Antigenic characteristics of the variants and their geographic distribution</title>
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<series><title level="j">Bulletin of the World Health Organization</title>
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<front><div type="abstract" xml:lang="en"><p>Outbreaks of influenza due to the virus A/Hong Kong/1/68 (H3N2) began in 1968 and are still occurring. The haemagglutinin of this virus is different from that of the A/Singapore/1/57 virus (the “Asian” strain) but the neuraminidase antigens are the same. Between 1968 and 1971 only minor antigenic “drift” in the haemagglutinin was noted, but in recent months 2 isolates have been identified in which considerable “drift” has occurred in the haemagglutinin and in the neuraminidase antigens. One, A/Hong Kong/5/72 (H3N2), was first detected in outbreaks in Hong Kong between November 1971 and January 1972 and was predominant there and in Korea but did not become widely disseminated. The second strain, A/England/42/72 (H3N2), has been isolated in winter outbreaks in the southern hemisphere and now appears to be the predominant strain in the northern hemisphere. The characteristics of the strains are described.</p>
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